TRIJARDY XR (empagliflozin/linagliptin) Patient Assistance Program
Don’t let the cost of brand triple-combination diabetes therapy disrupt your treatment. We help eligible patients access Trijardy XR (empagliflozin/linagliptin/metformin extended-release) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
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Key Takeaways:
- Trijardy XR is FDA-approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes when treatment with all three components is appropriate; the empagliflozin component also reduces the risk of cardiovascular death in adults with type 2 diabetes who have established cardiovascular disease.
- Without assistance, the average retail price runs approximately $520–$850 per month (30 tablets), and approximately $350–$520 per month with publicly listed coupons
- Through AffordMyPrescriptions, qualifying patients can access Trijardy XR for a flat $69.95 per month — our advocacy team manages the entire enrollment, refills, and renewal process.
- Generic empagliflozin, generic linagliptin, and generic metformin are all available as separate medicines at much lower cost; for many patients, taking the components separately may achieve the same therapeutic goal for a fraction of the price.
What is Trijardy XR Prescription Assistance Program?
The Trijardy XR Prescription Assistance Program is a manufacturer-sponsored initiative that provides Trijardy XR at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for adults with type 2 diabetes who are uninsured or underinsured and cannot afford brand triple-combination therapy.
Navigating the program on your own means dealing with eligibility verification, prescriber coordination, documentation requirements, and renewal deadlines — all while managing a chronic condition that requires consistent daily therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and annual re-certification — so you focus on your health, not paperwork..
Pharmacy Price Comparison
- Without assistance, Trijardy XR costs roughly $350–$850 per month at retail pharmacies. Discount coupons offer some relief, but they don't come close to what a Patient Assistance Program provides — if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$510.00 | Save ~$440/mo |
| CVS Pharmacy | ~$520.00 | Save ~$450/mo |
| Walmart | ~$420.00 | Save ~$350/mo |
| Costco | ~$385.00 | Save ~$315/mo |
| Kroger | ~$370.00 | Save ~$300/mo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Trijardy XR Prescription Program?
The Patient Assistance Program is free to apply for and provides Trijardy XR at little or no medication cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing renewal management. Our $69.95/month service covers full advocacy: applications, doctor coordination, documentation, refill management, and annual re-enrollment — so you focus on your health, not paperwork.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Trijardy XR:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
Coupon cards expire and require constant renewal
Still $350–$520 per month even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
If denied, we explore alternative savings paths on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Trijardy XR assistance.
- You are a U.S. citizen or legal resident
- You Have A Valid Trijardy XR Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Trijardy XR:
Trijardy XR (empagliflozin/linagliptin/metformin extended-release) is a once-daily oral combination tablet that combines three diabetes medicines — an SGLT2 inhibitor, a DPP-4 inhibitor, and metformin — in a single extended-release tablet. The maximum recommended dose is 25 mg empagliflozin / 5 mg linagliptin / 2,000 mg metformin per day. Trijardy XR is taken once daily with a meal in the morning, swallowed whole.
How It Works:
Trijardy XR manages type 2 diabetes by combining three distinct medications into a single tablet. Metformin reduces sugar release from the liver, empagliflozin helps the kidneys filter sugar into the urine, and linagliptin assists the pancreas in releasing more insulin. By targeting these different pathways simultaneously, the medication provides a comprehensive approach to lowering overall blood-sugar levels.
Form and Use:
This medication is taken as one tablet once daily with a morning meal. It is essential to swallow the tablet whole without splitting, crushing, dissolving, or chewing it to maintain its extended-release properties. The maximum daily dose is limited to 25 mg of empagliflozin, 5 mg of linagliptin, and 2,000 mg of metformin to ensure safe and effective treatment.
Generic Availability:
As of 2026, there is no FDA-approved generic version of the Trijardy XR combination tablet in the U.S. due to active patent protections. However, all three of its individual components are available as separate generic medicines, with metformin being particularly affordable. Patients may consult their doctors about whether taking these three generics separately could achieve the same treatment goals at a lower cost.
Warnings:
Trijardy XR is not for type 1 diabetes or ketoacidosis and is not recommended for patients with significantly reduced kidney function. It carries a boxed warning for lactic acidosis, a rare but serious condition linked to the metformin component. Doctors should assess a patient’s kidney function and volume status before starting the drug, especially in older adults or those taking diuretics.
FAQ (Frequently Asked Questions)
How Much Does Trijardy XR Cost Without Insurance?
The average retail price runs approximately $520–$850 per month, and approximately $350–$520 with publicly listed coupons depending on strength and pharmacy. Through AffordMyPrescriptions, qualifying patients receive Trijardy XR at no medication cost — our $69.95 monthly fee covers full advocacy and program management.
Why Does Trijardy XR Combine Three Medicines?
Trijardy XR puts an SGLT2 inhibitor, a DPP-4 inhibitor, and metformin into one extended-release daily tablet so patients do not have to take all three medicines separately. The three components work through different pathways, which can help lower blood sugar more than any one component alone.
Are There Cheaper Generic Alternatives I Should Know About?
Yes. Generic empagliflozin, generic linagliptin, and generic metformin are all available as separate medicines, and generic metformin in particular is among the cheapest prescription medications on the market. If you do not specifically need all three medicines combined into one tablet, your prescriber may be able to write the components separately as generics — typically dramatically cheaper than brand Trijardy XR. We mention this directly because for many patients, splitting the combination into generics is a better path than paying for our advocacy on the brand.
Who Should Not Take Trijardy XR?
Trijardy XR is not used in type 1 diabetes and is not used to treat diabetic ketoacidosis. Initiation is not recommended in patients with eGFR below 45 mL/min/1.73 m² because of the metformin component. Like all metformin-containing products, it carries a boxed warning for lactic acidosis.
What If My Application Is Denied?
If your initial application is denied, we explore alternative savings paths on your behalf — including the manufacturer’s copay savings card if you have commercial insurance, independent foundations such as the PAN Foundation or HealthWell Foundation for diabetes-related funds, or asking your prescriber whether splitting Trijardy XR into separate generic components would meet your treatment goals at much lower cost. If we cannot find a path to medication access, you will not be charged our service fee.
How Long Does It Take To Get Approved?
Most enrolled patients receive their first Trijardy XR shipment within two to four weeks of completing the documentation. Timing depends on how quickly your prescriber returns the required forms and the program processes your application.
Take Control of Your Medication Costs
If you are struggling with the high cost of Trijardy XR, our team may be able to help you access assistance programs designed to make brand triple-combination diabetes therapy affordable. Check your eligibility today and take the first step toward predictable, sustainable treatment.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.