SKYRIZI (risankizumab-rzaa) Patient Assistance Program
Don’t let chronic inflammatory disease rob you of your quality of life. We help eligible patients access Skyrizi (risankizumab-rzaa) for as little as $69.95 per month through manufacturer Patient Assistance Programs.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
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BBB Accredited
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Key Takeaways:
- Skyrizi Is An IL-23 Inhibitor Biologic Treating Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, And Ulcerative Colitis
- List Price Is Approximately $23,838 Per Dose, With Annual Treatment Costs Of Approximately $120,000
- AffordMyPrescriptions Provides Access To Skyrizi For Just $69.95/Month Through The Patient Assistance Program — Up To 12 Months Of Medication At No Cost For Qualifying Patients
- No Biosimilar Version Of Skyrizi Is Currently Available — Earliest Expected Biosimilar Not Anticipated Until Approximately 2031
What is Skyrizi Prescription Assistance Program?
The Skyrizi Prescription Assistance Program is a manufacturer-sponsored initiative that provides Skyrizi at no cost for up to 12 months to qualifying patients who cannot afford the medication. For commercially insured patients, a copay savings card can reduce out-of-pocket costs to as little as $0 per dose (with a maximum annual savings of $14,000). A separate patient assistance program is available for uninsured patients, those with limited insurance, or Medicare Part D patients who cannot afford their medication.
When your specialist prescribes Skyrizi because your inflammatory disease has failed to respond to conventional therapies, the promise of clearer skin, reduced joint destruction, or remission can feel life-changing. Then you learn the medication costs $23,838 per dose — nearly $120,000 per year — and the promise suddenly feels financially impossible.
AffordMyPrescriptions exists to bridge that gap. For a flat $69.95 per month, our Patient Advocates specialize in biologic medication access across all four conditions Skyrizi treats.
Pharmacy Price Comparison
- Without assistance, Skyrizi costs significantly more at retail pharmacies than through our advocacy service. Discount programs offer some relief, but they don't come close to what a Patient Assistance Program provides, if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$20,500.00 | Save ~$20,430/mo |
| CVS Pharmacy | ~$20,212.00 | Save ~$20,142/mo |
| Walmart | ~$20,400.00 | Save ~$20,330/mo |
| List Price | ~$23,838.00 | Save ~$23,768/mo |
| SingleCare | ~$10,094.00 | Save ~$10,024/mo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Skyrizi Prescription Program?
Biologic medications like Skyrizi involve a level of complexity that sets them apart from standard prescriptions — specialty pharmacy requirements, prior authorization battles, step therapy mandates, and annual re-enrollment processes. When your immune system is being managed by a biologic that costs $120,000 per year, losing access for even one missed dose can trigger a disease flare that takes months to bring back under control.
Our trained Patient Advocates understand the unique challenges of biologic medication access across dermatology, rheumatology, and gastroenterology. From the moment you enroll, your advocate navigates prior authorization and step therapy requirements, prepares your PAP application, coordinates with the specialty pharmacy, and tracks your approval status through every stage. When your next dose is due, they coordinate proactively to ensure seamless delivery.
Our pricing is simple and predictable: $69.95 per month — every month, without exception. While the medication itself is provided at no cost through the manufacturer’s program, our monthly fee covers all advocacy, application management, specialty pharmacy coordination, and refill oversight. If we’re unable to secure access, you won’t be charged.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through Afford My Prescriptions is the better long-term solution:
Limitations of Coupons
$0 copay card excludes Medicare/Medicaid/government insurance
- Even with copay card, $14,000 annual savings cap exists
- GoodRx coupons still cost $20,000+/dose — unaffordable for most
- Specialty pharmacy network may limit coupon applicability
- Prior authorization and step therapy requirements add delay
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- Up to 12 months of Skyrizi at no medication cost, renewable
- Medication supplied directly from the manufacturer
We manage all paperwork, refills, and annual renewals
- Medicare Part D patients accepted
DO YOU QUALIFY?
Eligibility is generally determined by annual household income levels. Most programs follow guidelines that include a limit of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Patients with Medicare Part D may also qualify.
- You are a U.S. citizen or legal resident
- You Have A Valid Skyrizi Prescription From A Licensed Specialist
- You Have Been Diagnosed With Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, Or Ulcerative Colitis
- You Are Uninsured, Underinsured, Or Have Experienced Financial Hardships
- Medicare Part D Patients Accepted
Understanding Skyrizi:
Skyrizi (risankizumab-rzaa) is a prescription biologic medication used to treat four inflammatory conditions in adults: moderate-to-severe plaque psoriasis, active psoriatic arthritis, moderately-to-severely active Crohn’s disease, and moderately-to-severely active ulcerative colitis. Skyrizi works by selectively targeting interleukin-23 (IL-23), a key protein that drives the inflammation underlying all four conditions.
How It Works:
Skyrizi is a monoclonal antibody that targets the IL-23 protein, a key driver of inflammation in conditions like plaque psoriasis and Crohn’s disease. By binding to the p19 subunit of this protein, the medication neutralizes the signal that activates inflammatory immune cells. This selective process helps break the cycle of chronic inflammation while leaving much of the broader immune system intact.
Form and Use:
The medication is administered via self-injection under the skin for skin and joint conditions, typically every three months after initial doses. For digestive conditions like Crohn’s or ulcerative colitis, treatment begins with intravenous infusions before transitioning to self-injections every two months. It is conveniently available in prefilled pens, syringes, or on-body injector devices.
Generic Availability:
There are currently no biosimilar versions of Skyrizi available in the United States, as biologics cannot have traditional generics. Due to existing patent protections, the earliest a biosimilar is expected to enter the market is approximately 2031. In the meantime, patient assistance programs can help provide the medication at a significantly reduced monthly cost.
Warnings:
Skyrizi can increase the risk of infections, so users should monitor for symptoms and consult a healthcare provider if they occur. It is important to avoid receiving live vaccines while using this medication. Common side effects may include headaches, injection site reactions, and upper respiratory tract infections.
FAQ (Frequently Asked Questions)
How Much Does Skyrizi Cost Without Insurance?
The list price of Skyrizi is approximately $23,838 per dose, with annual costs of approximately $120,000. The copay savings card offers $0 per dose for commercially insured patients ($14,000 annual max). The PAP provides up to 12 months free for qualifying patients. Through AffordMyPrescriptions, qualifying patients receive Skyrizi at no medication cost — our $69.95 monthly fee covers advocacy.
Is This The Same Skyrizi I'd Get At A Pharmacy?
Yes. The Skyrizi supplied through the Patient Assistance Program is the same FDA-approved risankizumab-rzaa medication dispensed at specialty pharmacies, supplied directly from the manufacturer.
How Often Do I Need To Take Skyrizi?
For plaque psoriasis and psoriatic arthritis: two initial doses one month apart, then one injection every 3 months. For Crohn’s disease and ulcerative colitis: three IV infusions over the first 3 months, then subcutaneous injections every 2 months.
Is There A Biosimilar Of Skyrizi?
Not yet. The earliest a Skyrizi biosimilar is expected to become available is approximately 2031, based on current patent protections.
Can I Get Skyrizi Through The PAP If I Have Medicare?
Yes. Medicare Part D patients may qualify for the Patient Assistance Program. As of 2026, Medicare Part D plans also have a $2,100 annual out-of-pocket cap. Our advocates can help you evaluate the best pathway.
What if my application is denied?
Our Patient Advocates will immediately explore every alternative — including the manufacturer’s $0 copay card ($14,000 annual max for commercially insured), insurance prior authorization appeals, step therapy completion documentation, biosimilar adalimumab as a less expensive biologic alternative, Otezla (apremilast) for psoriasis/PsA, and independent co-pay assistance foundations (PAN Foundation, HealthWell Foundation, National Psoriasis Foundation).
Take Control of Your Medication Costs
If you are struggling with the high cost of Skyrizi, our team may be able to help you access assistance programs designed to make medications more affordable. Check your eligibility today and take the first step toward reducing your prescription costs.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.