RECTIV Patient Assistance Program

Don’t let the cost of anal fissure treatment leave you in pain. We help eligible patients access Rectiv (nitroglycerin 0.4% ointment) for as little as $69.95 per month through
Patient Assistance Programs.

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Key ​Takeaways:

What is Rectiv Prescription Assistance Program?

The Rectiv Prescription Assistance Program is a manufacturer-sponsored initiative that provides Rectiv at no medication cost to qualifying patients. The program is available to uninsured and underinsured U.S. residents who meet income and residency requirements. If approved, you receive your medication at no cost.

Chronic anal fissure pain is one of the most intense forms of pain patients experience — a sharp, searing sensation during bowel movements that can persist for hours afterward, making it impossible to concentrate, work, or sleep comfortably. When the only FDA-approved treatment for this condition
costs $508 or more per tube, patients face an agonizing dilemma.

AffordMyPrescriptions eliminates that impossible choice. For a flat $69.95 per month, our Patient Advocates manage every step of your enrollment, from initial application through ongoing access — with complete discretion.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens

~$165.00

Save ~$95/mo
CVS Pharmacy

~$158.11

Save ~$88/mo

Walmart

~$150.00

Save ~$80/mo

SingleCare Best Price

~$155.71

Save ~$86/mo

Kroger

~$160.00

Save ~$90/mo

*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.

Our Pricing:

Our advocacy service pricing is simple and predictable. The cost is based on the number of medications enrolled in our service — not on the retail price of your prescriptions. Most patients pay just $69.95/month for full advocacy on a single medication.

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Rectiv Prescription Program?

Anal fissure pain is intensely personal and often embarrassing to discuss, which means many patients suffer in silence rather than seeking help navigating the complex and expensive treatment landscape. When your doctor prescribes Rectiv and you discover it costs $500 or more — for a condition you may feel uncomfortable even mentioning at the pharmacy counter — the barriers to getting treatment can feel insurmountable.

From the moment you enroll, your advocate takes full ownership of your case. They prepare your application, coordinate with your gastroenterologist or colorectal specialist to gather required documentation, and track approval through every stage. They can also help identify pharmacies that stock Rectiv in your area, since many retail pharmacies do not routinely carry it. If your treatment requires additional tubes, they manage refill coordination proactively.

Our pricing is simple and predictable: $69.95 per month — every month, without exception. While the medication itself is provided at no cost through the assistance program, our monthly fee covers professional advocacy, application management, doctor coordination, and pharmacy coordination. If
we’re unable to secure access, you won’t be charged. And if a compounded alternative would serve your needs at a lower cost, we’ll discuss that option with you as well.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through Afford My Prescriptions is the better long-term solution:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward deductible
  • Cards expire and require constant renewal
  • Still $93–$303 per tube with best discount
  • Cannot be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95 for the treatment course — never changes
  • No expiration — continuous access as long as you qualify
  • Brand Rectiv supplied at no medication cost when approved
  • We help locate pharmacies that stock Rectiv in your area
  • We manage all paperwork, refills, and renewals

DO YOU QUALIFY?

Eligibility is generally determined by annual household income levels. Most programs follow guidelines that include a limit of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because these requirements can vary, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for assistance.

Understanding Rectiv:

Rectiv (nitroglycerin 0.4% ointment) is a prescription rectal ointment used to treat moderate to severe pain caused by chronic anal fissures in adults. An anal fissure is a small tear in the skin lining the anal canal that causes sharp, often debilitating pain during and after bowel movements. Rectiv is the only FDA-approved 0.4% nitroglycerin rectal ointment in the United States. It is applied inside the anal canal every 12 hours for up to three weeks.


How It Works:

Rectiv treats chronic anal fissures by delivering nitroglycerin directly to the internal anal sphincter muscle. This releases nitric oxide, which relaxes the muscle and breaks the cycle of painful spasms that prevent healing. By reducing tension and increasing blood flow to the site of the tear, the ointment creates the necessary conditions for the skin to repair itself.

 

Form and Use:

Patients should apply roughly one inch of ointment inside the anal canal every 12 hours for a period of up to three weeks. It is recommended to use a finger covering, such as a glove or plastic wrap, during application to ensure proper hygiene and dosing. Once the tube is opened, the medication remains effective for 8 weeks before it should be discarded.

Generic Availability:

There is currently no FDA-approved generic version of Rectiv available as of April 2026. However, patients may access compounded nitroglycerin or diltiazem ointments from specialized pharmacies at a significantly lower cost, typically between $30 and $100. While these compounded alternatives are more affordable, they are not FDA-approved and may vary in consistency.


Warnings:

The most frequent side effect reported is headaches, particularly during the initial stages of treatment. It is critical to avoid alcohol and PDE5 inhibitors like sildenafil or tadalafil while using Rectiv, as these combinations can lead to dangerously low blood pressure. Patients with existing heart conditions or those taking blood pressure medications should consult their doctor before use.

FAQ (Frequently Asked Questions)

How much does Rectiv cost without insurance?

The average retail price is approximately $508–$829 per 30-gram tube. With GoodRx coupons, the lowest price is approximately $93.02, though typical coupon prices range from $150 to $303. Through AffordMyPrescriptions, qualifying patients receive Rectiv at no medication cost
— our $69.95 monthly fee covers advocacy and program management.

Yes. The Rectiv provided through the Patient Assistance Program is the identical FDA- approved 0.4% nitroglycerin rectal ointment that would be dispensed at any retail or specialty pharmacy.

No FDA-approved generic exists. However, compounded nitroglycerin 0.2%–0.4% ointment can be prepared by compounding pharmacies at significantly lower cost ($30–$100), though it is not FDA-approved. Our advocates can discuss this option with your doctor if appropriate.

Our Patient Advocates will immediately explore every alternative — including GoodRx and SingleCare coupons ($93–$303 per tube), compounded nitroglycerin ointment from a local compounding pharmacy ($30–$100), compounded diltiazem 2% ointment, insurance prior authorization appeals, and other treatment options your doctor may recommend. If we cannot secure assistance, you won’t be charged.

This is a common problem. Most retail chain pharmacies do not routinely stock Rectiv due to its niche indication. Our Patient Advocates can help identify pharmacies in your area that carry or can order Rectiv, saving you the frustration of calling multiple locations.

Most applications are processed within 2–4 weeks. Because anal fissure pain is severe and Rectiv treatment is time-limited (up to 3 weeks), our advocates prioritize rapid processing.

Take Control of Your Medication Costs

If you are struggling with the high cost of Rectiv, our team may be able to help you
access assistance programs designed to make medications more affordable. Check
your eligibility today and take the first step toward reducing your prescription costs.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process