HARVONI (ledipasvir/sofosbuvir) Patient Assistance Program
Don’t let the high cost of brand chronic hepatitis C therapy disrupt your treatment. We help eligible patients access Harvoni (ledipasvir/sofosbuvir) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
HIPAA Compliant
BBB Accredited
Secure Website
Key Takeaways:
- Harvoni (ledipasvir/sofosbuvir) is a once-daily, fixed-dose direct-acting antiviral (DAA) regimen FDA-approved for chronic hepatitis C virus (HCV) genotype 1, 4, 5, or 6 in adults and pediatric patients (≥3 years).
- Without assistance, brand Harvoni costs commonly run approximately $30,000–$33,000 per 28-day supply, with a typical 12-week course commonly $90,000–$100,000+.
- Through AffordMyPrescriptions, qualifying patients can access Harvoni for a flat $69.95 per month — our advocacy team manages the entire enrollment, refills, and renewal process.
- An authorized generic of ledipasvir/sofosbuvir is now available at substantially lower cost (commonly $24,000/course list, with state Medicaid and pricing programs much lower). For pan-genotypic coverage, generic sofosbuvir/velpatasvir (Epclusa equivalent) or Mavyret are widely used.
What Is Harvoni Prescription Assistance Program?
The Harvoni Prescription Assistance Program is a manufacturer-sponsored initiative that provides Harvoni at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for chronic hepatitis C patients who are uninsured or underinsured, as well as Medicare Part D beneficiaries.
Navigating the program on your own means dealing with eligibility verification, hepatologist or HCV provider coordination, prior-authorization documentation, and renewal deadlines.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and treatment-course completion.
Pharmacy Price Comparison
- Without assistance, brand Harvoni costs roughly $30,000–$33,000/month. A Patient Assistance Program is the meaningful path forward — if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens (brand) | ~$32,000 | Save ~$31,930/mo |
| CVS Pharmacy (brand) | ~$33,000 | Save ~$32,930/mo |
| Walmart (brand) | ~$30,500 | Save ~$30,430/mo |
| Costco (brand) | ~$30,000 | Save ~$29,930/mo |
| Authorized generic | ~$8,000 | Authorized generic |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Harvoni Prescription Program?
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Harvoni:
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Epclusa:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $30,000–$33,000 per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Harvoni assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Harvoni Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Harvoni:
Harvoni (ledipasvir/sofosbuvir) is a once-daily, fixed-dose two-drug DAA combination for chronic hepatitis C genotypes 1, 4, 5, and 6. It combines an NS5A inhibitor (ledipasvir) and an NS5B nucleotide polymerase inhibitor (sofosbuvir) for highly effective combination therapy.
How Harvoni Works:
Harvoni utilizes two direct-acting antivirals, ledipasvir and sofosbuvir, to disrupt the Hepatitis C virus replication cycle. Ledipasvir inhibits the NS5A protein to block viral RNA assembly, while sofosbuvir targets the NS5B polymerase to terminate the synthesis of the viral RNA chain. This combined approach achieves a cure rate of over 95% in treatment-naïve genotype 1 patients by attacking the virus from multiple angles.
Form and use:
The medication is administered as a single oral tablet taken once daily, with or without food. The standard treatment course typically lasts between 8 to 12 weeks, with the specific duration determined by the patient’s genotype, cirrhosis status, and prior treatment history. Most patients successfully achieve a complete cure after completing just one course of therapy.
Generic availability:
An authorized generic version of ledipasvir/sofosbuvir is currently available in the U.S., offering a significantly more affordable option than the brand-name Harvoni. While Harvoni is effective for specific genotypes, other pan-genotypic options like generic Epclusa or Mavyret are also widely utilized. Many state programs and initiatives have negotiated lower pricing to make these curative treatments more accessible.
Warnings:
Harvoni includes a critical warning regarding Hepatitis B reactivation, necessitating HBV testing for all patients before beginning treatment to avoid potentially fatal flares. It can also cause serious bradycardia if taken with amiodarone and may be rendered ineffective by strong P-gp or CYP inducers like rifampin or St. John’s wort. Patients must be screened for these drug interactions to ensure the medication remains effective and safe.
FAQ (Frequently Asked Questions)
How Much Does Harvoni Cost Without Insurance?
Brand Harvoni costs approximately $30,000–$33,000 per 28-day supply. Authorized generic ledipasvir/sofosbuvir is dramatically cheaper. Through AffordMyPrescriptions, qualifying patients receive Harvoni at no medication cost — our $69.95 monthly fee covers full advocacy and program management.
Will I Be Cured After Harvoni Treatment?
Yes, in most cases. Harvoni cures over 95% of HCV genotype 1 (and most genotype 4, 5, 6) patients in 8–12 weeks. ‘Cure’ in HCV means sustained virologic response 12 weeks after completing therapy (SVR12) — a durable, treatment-ending outcome.
Is The Authorized Generic Of Harvoni The Same?
Yes. An authorized generic is the brand product, sold under a different (generic) name and label. The active ingredients, doses, manufacturing, and clinical effect are the same. The authorized generic of ledipasvir/sofosbuvir is widely accepted as clinically equivalent to Harvoni and is substantially cheaper.
How Is Harvoni Different From Epclusa?
Both are sofosbuvir-based DAA combinations. Harvoni (ledipasvir/sofosbuvir) covers HCV genotypes 1, 4, 5, 6. Epclusa (velpatasvir/sofosbuvir) is pan-genotypic — it covers all HCV genotypes (1–6). Most U.S. patients with genotype 1 do well on either. Epclusa is usually preferred when the genotype is unknown or when treating non-genotype-1.
Can I Get Harvoni Through The PAP If I Have Medicare?
Yes. An authorized generic is the brand product, sold under a different (generic) name and label. The active ingredients, doses, manufacturing, and clinical effect are the same. The authorized generic of sofosbuvir/velpatasvir is widely accepted as clinically equivalent to Epclusa and is substantially cheaper.
What If I Have Hepatitis B Co-infection?
Tell your prescriber. HCV treatment with DAAs can cause severe hepatitis B reactivation in patients with chronic HBV. HBV testing is required before starting, and HBV co-infection requires a coordinated treatment plan.
What If My Application Is Denied?
If denied, we explore alternatives — switching to the authorized generic of ledipasvir/sofosbuvir, generic sofosbuvir/velpatasvir (Epclusa equivalent), or Mavyret, state Medicaid for chronic HCV (now widely covered), the manufacturer’s copay program for commercially insured patients, or independent foundations. If we cannot find a path, you won’t be charged our service fee.
Take Control of Your Medication Costs
If you are struggling with the high cost of Harvoni, our team may be able to help you access assistance programs designed to make brand HCV cures affordable. Check your eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.