GLYXAMBI (empagliflozin/linagliptin) Patient Assistance Program

Don’t let the cost of brand combination diabetes therapy disrupt your treatment. We help eligible patients access Glyxambi (empagliflozin/linagliptin) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

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Key ​Takeaways:

What is Glyxambi Prescription Assistance Program?

The Glyxambi Prescription Assistance Program is a manufacturer-sponsored initiative that provides Glyxambi at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for adults with type 2 diabetes who are uninsured or underinsured and cannot afford brand combination therapy.

Navigating the program on your own means dealing with eligibility verification, prescriber coordination, documentation requirements, and renewal deadlines — all while managing a chronic condition that requires consistent daily therapy.

AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and annual re-certification — so you focus on your health, not paperwork.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens

~$370.00

Save ~$300/mo

CVS Pharmacy

~$372.00

Save ~$302/mo

Walmart

~$355.00

Save ~$285/mo

Costco

~$352.00

Save ~$282/mo

Kroger

~$358.00

Save ~$288/mo

*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Glyxambi Prescription Program?

The Patient Assistance Program is free to apply for and provides Glyxambi at little or no medication cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing renewal management. Our $69.95/month service covers full advocacy: applications, doctor coordination, documentation, refill management, and annual re-enrollment — so you focus on your health, not paperwork.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Glyxambi:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward your deductible

  • Coupon cards expire and require constant renewal
  •   Still $350–$370 per month even with the best discount

  • Cannot be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price

  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program

  • We manage all paperwork, refills,
    autoinjector coordination, and annual renewals
  • If denied, we explore alternative savings paths on your behalf

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Glyxambi assistance.

Understanding Glyxambi:

Glyxambi (empagliflozin/linagliptin) is a once-daily oral combination tablet for adults with type 2 diabetes. It combines an SGLT2 inhibitor (empagliflozin) and a DPP-4 inhibitor (linagliptin) in a single pill, in either 10 mg/5 mg or 25 mg/5 mg strengths. Glyxambi is not used in type 1 diabetes, is not used to treat diabetic ketoacidosis, and is not recommended for patients with severe kidney impairment (eGFR below ~30 mL/min/1.73 m²).


How It Works:

Glyxambi combines two medicines to lower blood sugar by targeting different body functions. The empagliflozin component helps the kidneys filter sugar out of the bloodstream and into the urine, while the linagliptin component helps the pancreas release more insulin. Together, these actions reduce the amount of sugar reabsorbed by the body and manage hormone levels to keep blood sugar in check.

Form and Use:

This medication is taken as a single tablet once daily in the morning and can be consumed with or without food. The standard starting dose is 10 mg / 5 mg, though a healthcare provider may increase this to 25 mg / 5 mg if better blood-sugar control is required. It provides a streamlined way to take two different types of diabetes medication at once.

Generic Availability:

As of 2026, a generic version of the combined Glyxambi tablet does not exist in the U.S. However, both active ingredients are available as individual generic medications. If the brand-name drug is too expensive, doctors may prescribe the two components separately as generic tablets to help significantly reduce out-of-pocket costs.

Warnings:

Glyxambi is not intended for type 1 diabetes, ketoacidosis, or patients with severe kidney impairment. Key risks include pancreatitis, which causes severe abdominal pain, and an increased risk of low blood sugar if used alongside insulin. It is important to consult a prescriber if serious symptoms occur or if you have a history of kidney issues.

FAQ (Frequently Asked Questions)

How Much Does Glyxambi Cost Without Insurance?

The average retail price is approximately $480–$870 per month for a 30-tablet supply. With the best GoodRx coupons, prices range $350–$370 at major pharmacies. Through AffordMyPrescriptions, qualifying patients receive Glyxambi at no medication cost — our $69.95 monthly fee covers full advocacy and program management

Yes. The Glyxambi supplied through the assistance program is the identical FDA-approved empagliflozin/linagliptin combination tablet you would receive at a retail pharmacy — same active ingredients, same dose strengths, same packaging.

Yes. Generic empagliflozin and generic linagliptin are both available as separate medicines, and many other generic diabetes medicines are widely available at low cost. If you do not specifically need both components in a single tablet, your prescriber may be able to write the components separately as generics — typically much cheaper than brand Glyxambi. We mention this directly because for many patients, splitting the combination into generics is a better path than paying for our advocacy on the brand.

Glyxambi is not used in type 1 diabetes and is not used to treat diabetic ketoacidosis. It is not recommended in patients with severe kidney impairment (eGFR below ~30 mL/min/1.73 m²) because the empagliflozin component is unlikely to improve glycemic control at that level of kidney function.

If your initial application is denied, we explore alternative savings paths on your behalf — including independent foundations such as the PAN Foundation or HealthWell Foundation for diabetes-related funds, the manufacturer’s copay savings card if you have commercial insurance ($10/fill reported), or asking your prescriber whether splitting Glyxambi into generic components would meet your treatment goals at much lower cost. If we cannot find a path to medication access, you will not be charged our service fee.

Most enrolled patients receive their first Glyxambi shipment within two to four weeks of completing the documentation. Timing depends on how quickly your prescriber returns the required forms and the program processes your application.

Take Control of Your Medication Costs

If you are struggling with the high cost of Glyxambi, our team may be able to help you access assistance programs designed to make brand combination diabetes therapy affordable. Check your eligibility today and take the first step toward predictable, sustainable treatment.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process