AUGTYRO (repotrectinib) Patient Assistance Program

Don’t let the high cost of targeted oncology therapy stand between you and the treatment you need. We help eligible patients access Augtyro (repotrectinib) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

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Key ​Takeaways:

What is Augtyro Prescription Assistance Program?

The Augtyro Prescription Assistance Program is a manufacturer-sponsored initiative that provides Augtyro at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for uninsured and underinsured individuals, as well as Medicare Part D beneficiaries who cannot afford their targeted oncology therapy.

Navigating the program on your own means dealing with eligibility verification, oncology-team coordination, ROS1/NTRK molecular testing documentation, specialty pharmacy logistics, and renewal deadlines — all while managing advanced cancer treatment.

AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through refill coordination and annual re-certification — so you focus on your treatment, not paperwork.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens

~$32,300.00

Save ~$32,230/mo

CVS Pharmacy

~$32,500.00

Save ~$32,430/mo

Walmart

~$30,500.00

Save ~$30,430/mo

Costco

~$29,800.00

Save ~$29,730/mo

Specialty Pharmacy

~$30,000.00

Save ~$29,930/mo

*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Augtyro Prescription Program?

The Patient Assistance Program is free to apply for and provides Augtyro at no medication cost if approved. But the process involves detailed applications, oncology-team coordination, molecular testing documentation, and limited specialty pharmacy logistics. Our $69.95/month service covers full advocacy: applications, doctor coordination, documentation, refill management, and annual re-enrollment — so you focus on your treatment, not paperwork.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Augtyro:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month

  •  Copay accumulators may prevent savings from counting toward your deductible

  • Coupon cards expire and require constant renewal

  • Still $30,000–$32,500 per month even with the best discount

  • Cannot be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price

  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program

  • We manage all paperwork, refills, and annual renewals

  • Medicare Part D patients accepted

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Augtyro assistance.

Understanding Augtyro:

Augtyro (repotrectinib) is an oral, targeted oncology medicine used to treat advanced cancers driven by specific genetic changes — ROS1-positive non-small cell lung cancer (NSCLC) and certain solid tumors that test positive for an NTRK gene fusion. Both indications require molecular testing to confirm the targetable genetic change before therapy is started.


How It Works:

Some cancers are driven by overactive signaling from ROS1 and TRK proteins, which become permanently “switched on” due to gene rearrangements or fusions. Augtyro is a small-molecule inhibitor that binds to these proteins and blocks their activity, effectively cutting off the growth signals for cancer cells. It is specifically engineered to remain effective even if the cancer develops resistance mutations against earlier-generation treatments.

Form and Use:

The standard treatment begins with a ramp-up phase of 160 mg once daily for the first 14 days, followed by an increase to 160 mg twice daily. The capsules must be swallowed whole and can be taken with or without food, though they should never be crushed or dissolved. Depending on how a patient tolerates the medication, an oncology team may choose to pause therapy or adjust the dosage.

Generic Availability:

As of 2026, there is no FDA-approved generic version of Augtyro available in the United States due to active patent protections. While other targeted therapies like entrectinib or larotrectinib exist, the choice between them depends on specific genetic factors and prior treatment history. Patients should consult their medical team to determine which targeted therapy is the most appropriate for their specific condition.

Warnings:

The FDA label includes significant warnings regarding central nervous system effects, such as dizziness, cognitive changes, and sleep disturbances, which affect a majority of patients. Other serious risks include lung inflammation (pneumonitis) and elevated liver enzymes. Patients must avoid using certain other medications, specifically CYP3A inhibitors, and should report all current drugs to their oncology team to prevent dangerous interactions.

FAQ (Frequently Asked Questions)

How Much Does Augtyro Cost Without Insurance?

The wholesale acquisition cost is approximately $29,000 per 30-day supply at the standard maintenance dose, and publicly listed coupon prices at major pharmacies generally fall in the range of $30,000–$32,500 per month. Through AffordMyPrescriptions, qualifying patients receive Augtyro at no medication cost — our $69.95 monthly fee covers full advocacy and program management.

ROS1 and NTRK gene rearrangements are confirmed through molecular testing of the tumor, often a next-generation sequencing panel performed on a biopsy or surgical specimen. Augtyro is approved only for tumors that have been confirmed ROS1-positive or NTRK fusion-positive on that kind of testing

Yes. Other approved options include crizotinib (used in ROS1-positive NSCLC), entrectinib (approved for ROS1-positive NSCLC and NTRK fusion-positive solid tumors), and larotrectinib (approved for NTRK fusion-positive solid tumors). Whether any is a clinical fit depends on the specific genetic change, your prior treatments, and other factors. We mention this directly because if a different therapy on a more accessible assistance pathway would work for your situation, that may be a better path.

Yes. Medicare Part D beneficiaries can typically qualify for Augtyro Patient Assistance, especially if you face specialty-tier copays you cannot afford. The manufacturer’s commercial copay savings program ($0 per month for eligible patients) is reserved for commercially insured patients only — but the underlying PAP supports Medicare patients who meet income criteria

If your initial application is denied, we explore alternative savings paths on your behalf — including independent oncology-focused foundations such as the PAN Foundation or HealthWell Foundation, disease-specific groups such as the ROS1ders or GO2 for Lung Cancer, the manufacturer’s copay savings program if you have commercial insurance, or asking your oncology team whether a different targeted therapy would be a clinical option for you. If we cannot find a path to medication access, you will not be charged our service fee.

Most enrolled patients receive their first Augtyro shipment within two to four weeks of completing the documentation. Augtyro is dispensed through a limited specialty pharmacy distribution network, so timing also depends on how quickly the specialty pharmacy completes intake and benefits investigation.

Take Control of Your Medication Costs

If you are struggling with the high cost of Augtyro, our team may be able to help you access assistance programs designed to make targeted oncology therapy affordable. Check your eligibility today and take the first step toward predictable, sustainable treatment.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process