VITRAKVI (larotrectinib) Patient Assistance Program
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
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Key Takeaways:
- Vitrakvi (larotrectinib) is FDA-approved for adult and pediatric patients with solid tumors that have an NTRK gene fusion, that are metastatic or where surgical resection would result in severe morbidity, and who have no satisfactory alternative treatments or have progressed on prior therapy.
- Without assistance, the retail cost commonly runs $30,000–$42,000 per 30-day supply at the standard adult dose. Annual costs commonly land between $360,000 and $500,000.
- Through AffordMyPrescriptions, qualifying patients can access Vitrakvi for a flat $69.95 per month — our advocacy team manages the entire enrollment, refills, and renewal process.
- There is no generic version of Vitrakvi available in the U.S. as of 2026.
What is Vitrakvi Prescription Assistance Program?
The Vitrakvi Prescription Assistance Program is a manufacturer-sponsored initiative that provides Vitrakvi at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for uninsured and underinsured individuals, as well as Medicare Part D beneficiaries who cannot afford their targeted oncology therapy.
Navigating the program on your own means dealing with eligibility verification, oncology-team coordination, NTRK molecular testing documentation, specialty pharmacy logistics, and renewal deadlines — all while managing a serious cancer diagnosis.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through refill coordination and annual re-certification — so you focus on your treatment, not paperwork.
Pharmacy Price Comparison
- Without assistance, Vitrakvi costs roughly $30,000–$42,000 per 30-day supply at retail pharmacies. Discount coupons offer little relief at this price level. A Patient Assistance Program is the meaningful path forward — if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$41,500.00 | Save ~$41,430/mo |
| CVS Pharmacy | ~$41,800.00 | Save ~$41,730/mo |
| Walmart | ~$32,500.00 | Save ~$32,430/mo |
| Costco | ~$31,500.00 | Save ~$31,430/mo |
| Kroger | ~$33,000.00 | Save ~$32,930/mo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Vitrakvi Prescription Program?
The Patient Assistance Program is free to apply for and provides Vitrakvi at no medication cost if approved. But the process involves detailed applications, oncology-team coordination, NTRK fusion documentation, specialty pharmacy logistics, and ongoing renewal management. Our $69.95/month service covers full advocacy: applications, doctor coordination, molecular-testing documentation, refill management, and annual re-enrollment — so you focus on your treatment, not paperwork
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Vitrakvi:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
Coupon cards expire and require constant renewal
Still $30,000–$42,000 per month even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
Medicare Part D patients accepted
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Vitrakvi assistance.
- You are a U.S. citizen or legal resident
- You Have A Valid Vitrakvi Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Vitrakvi:
Vitrakvi (larotrectinib) is an oral, targeted oncology medicine used to treat adult and pediatric patients with solid tumors that have a specific genetic change called an NTRK gene fusion. It is unusual among cancer medicines because it is approved based on the genetic change driving the tumor, not the location of the tumor in the body. Eligibility requires a confirmed NTRK fusion-positive tumor on molecular testing
How It Works:
Vitrakvi is a targeted therapy designed to block a specific group of proteins known as TRKA, TRKB, and TRKC. In certain cancers, an abnormal gene fusion causes these proteins to stay permanently switched on, which forces cancer cells to grow and divide uncontrollably. By blocking these signals, Vitrakvi interrupts the growth process across various tumor types, regardless of where the cancer originated in the body.
Form and Use:
For adults, the standard dose is 100 mg taken by mouth twice daily, available as either capsules or an oral solution. Pediatric doses are calculated based on weight and are also administered twice a day, with a specific cap per dose. This medication can be taken with or without food, and your oncology team may adjust the dosage based on your liver function, kidney health, or potential drug interactions.
Generic Availability:
As of 2026, there is no FDA-approved generic version of Vitrakvi in the United States, as patent and exclusivity protections are still in effect. While other TRK-targeted therapies like entrectinib exist and may serve as alternatives in certain clinical situations, these decisions are handled by your oncology team. Choice of therapy depends on factors such as tumor type, treatment history, and whether the cancer involves the central nervous system.
Warnings:
Before starting Vitrakvi, molecular testing must confirm the presence of an NTRK gene fusion in the tumor. While common side effects include fatigue, nausea, and dizziness, the drug also carries risks for liver toxicity, bone fractures, and neurologic effects like mood changes. Your oncology team will provide continuous monitoring and may modify your dose to manage these risks or any increased liver enzymes.
FAQ (Frequently Asked Questions)
How Much Does Vitrakvi Cost Without Insurance?
The retail price commonly runs $30,000–$42,000 per 30-day supply at the standard adult dose. Coupon discounts exist but are modest because the underlying price is so high. Through AffordMyPrescriptions, qualifying patients receive Vitrakvi at no medication cost — our $69.95 monthly fee covers full advocacy and program management.
Is This The Same Vitrakvi I'd Get At A Pharmacy?
Yes. The Vitrakvi supplied through the assistance program is the identical FDA-approved larotrectinib (capsules or oral solution) you would receive at a retail pharmacy — same active ingredient, same formulation, same packaging.
How Is The Diagnosis Of NTRK Fusion Confirmed?
An NTRK gene fusion is confirmed through molecular testing of the tumor, often a next-generation sequencing panel performed on a biopsy or surgical specimen. Vitrakvi is only used in patients whose tumor has been confirmed NTRK fusion-positive on that kind of testing.
Is There A Generic Version Of Vitrakvi?
No. There is no generic version of Vitrakvi available in the U.S. as of 2026. Entrectinib is another approved TRK inhibitor used in some NTRK fusion cancers — whether it would be a clinical fit depends on tumor type, prior treatment, and central-nervous-system involvement, and the choice belongs with your oncology team.
Can I Get Vitrakvi Through The PAP If I Have Medicare?
Yes. Medicare Part D beneficiaries can typically qualify for Vitrakvi Patient Assistance, especially if you face specialty-tier copays you cannot afford. The manufacturer’s commercial copay savings program ($0 per fill, up to ~$25,000/year) is reserved for commercially insured patients only — but the underlying PAP supports Medicare patients who meet income criteria.
What If My Application Is Denied?
If your initial application is denied, we explore alternative savings paths on your behalf — including independent oncology-focused foundations such as the PAN Foundation or HealthWell Foundation, tumor-type-specific resources for sarcoma or rare cancers, the manufacturer’s copay savings program if you have commercial insurance, or asking your oncology team whether a different TRK inhibitor would be a clinical option for you. If we cannot find a path to medication access, you will not be charged our service fee.
Take Control of Your Medication Costs
If you are struggling with the high cost of Vitrakvi, our team may be able to help you access assistance programs designed to make targeted oncology therapy affordable. Check your eligibility today and take the first step toward predictable, sustainable treatment.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.