CALQUENCE Patient Assistance Program
Don’t let the cost of targeted cancer therapy come between you and treatment. We help eligible patients access Calquence (acalabrutinib) for as little as $69.95 per month through manufacturer Patient Assistance Programs.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
HIPAA Compliant
BBB Accredited
Secure Website
Key Takeaways:
- Calquence Is A Next-Generation Oral BTK Inhibitor And A First-Choice Treatment For CLL/SLL — Providing Targeted Cancer Cell Control For Blood Cancers
- Retail Price Is Approximately $15,934 Per Month Without Insurance (60 Tablets At 100 mg Twice Daily), Totaling Over $191,000 Per Year
- AffordMyPrescriptions Provides Access To Calquence For Just $69.95/Month Through The Patient Assistance Program
- No Generic Version Of Calquence Is Available In U.S. Pharmacies — The Medication Remains Patent-Protected
What is Calquence Prescription Assistance Program?
The Calquence Prescription Assistance Program is a manufacturer-sponsored initiative that provides Calquence at no medication cost to patients who qualify based on income and insurance status. The program is designed for uninsured and underinsured individuals, as well as patients denied insurance coverage. Medicare Part D patients may also qualify on a case-by- case basis. If approved, you receive your medication free of charge through a specialty pharmacy, and you can reapply as needed for continued access.
Navigating this program on your own, however, means dealing with eligibility requirements, oncologist coordination, specialty pharmacy logistics, and annual re-enrollment deadlines — all while fighting a blood cancer that demands uninterrupted treatment.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refills and annual re-enrollment, so you can focus entirely on your cancer treatment.
Pharmacy Price Comparison
- Without assistance,Armour Thyroid can cost hundreds — or even thousands — of dollars per month at retail pharmacies. Discount programs offer some relief, but they don't come close to what a Patient Assistance Program provides, if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$15,950.00 | Save ~$15,880/mo |
| CVS Pharmacy | ~$15,934.00 | Save ~$15,864/mo |
| Walmart | ~$15,945.00 | Save ~$15,875/mo |
| Costco | ~$15,920.00 | Save ~$15,850/mo |
| Kroger | ~$15,938.00 | Save ~$15,868/mo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. Afford My Prescriptions Advocacy Service bypasses retail pricing by using drug manufacturer programs to secure your medication for you—independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Calquence Prescription Program?
The Patient Assistance Program is free to apply for and provides medication at no cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing management. Our $69.95/month covers full advocacy: applications, doctor coordination, documentation, refill management, and re-enrollment — so you focus on your health, not paperwork.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through Afford My Prescriptions is the better long-term solution:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Cards expire and require constant renewal
- Subject to strict monthly or annual maximum savings caps
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly from the manufacturer
- We manage all paperwork, refills, and renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income levels. Most programs follow guidelines that include a limit of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because these requirements can vary, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for assistance.
- You are a U.S. citizen or legal resident
- You Have A Valid Besivance Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication At Current Pharmacy Prices
- You Are Enrolled In Medicare Part D (Case-By-Case Eligibility)
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Calquence:
Calquence (acalabrutinib) is a prescription oral tablet used to treat adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and mantle cell lymphoma (MCL). It is a second-generation BTK (Bruton’s tyrosine kinase) inhibitor — a targeted cancer therapy taken by mouth twice daily (100 mg approximately every 12 hours), with or without food. Calquence can be used alone or in combination with other treatments and is considered a first- choice treatment option for CLL. It is a specialty medication dispensed through specialty pharmacies.
How It Works:
Blood cancers like CLL, SLL, and mantle cell lymphoma develop when certain white blood cells (B-cells) begin growing out of control and accumulating in the blood, bone marrow, and lymph nodes. These cancerous B-cells depend on a signaling pathway driven by an enzyme called Bruton’s tyrosine kinase (BTK) to receive the survival and growth signals that keep them alive and dividing.
Calquence works by selectively and permanently binding to the BTK enzyme, blocking it from functioning. Think of BTK as a switch that cancer cells flip to receive "grow and survive" signals. By permanently disabling this switch, Calquence cuts off the survival signals cancer cells need to thrive. Without these signals, the cancer cells stop multiplying and eventually die. Calquence was designed as a second-generation BTK inhibitor — engineered to bind more selectively to BTK and less to other similar proteins in the body, compared to first-generation BTK inhibitors. This selectivity is intended to maintain powerful anti-cancer activity while reducing certain off- target effects.
Form and Use:
Available as 100 mg tablets. Take one tablet twice daily (approximately every 12 hours), with or without food. Swallow whole — do not crush, break, or chew. Treatment continues as long as my our oncologist determines the medication is providing benefit.
Generic Availability:
As of April 2026, there is no generic version of Calquence (acalabrutinib) available in the United States. Calquence remains patent-protected, and no FDA-approved generic has been authorized. Alternative BTK inhibitors such as ibrutinib and zanubrutinib treat similar indications but are also brand-only drugs at similar price points. Until a generic becomes available, the Patient Assistance Program through AffordMyPrescriptions provides the most affordable access pathway.
Warnings:
Do not stop taking Calquence without first talking to your oncologist — interrupting BTK inhibitor therapy can allow disease to progress. Calquence can increase the risk of bleeding and infections. Tell your doctor about all medications you take, especially blood thinners. Report unusual bleeding, fever, or signs of infection immediately. Regular blood tests will monitor your response and safety.
FAQ (Frequently Asked Questions)
How Much Does Calquence Cost Without Insurance?
Calquence costs approximately $15,934 per month for 60 tablets of 100 mg — over $191,000 per year. The manufacturer offers a $0 copay program for commercially insured patients. Medicare Part D plans include a $2,100 annual out-of-pocket cap in 2026. Through AffordMyPrescriptions, qualifying patients receive Calquence at no medication cost — our $69.95 monthly fee covers advocacy and program management.
Is This The Same Calquence I'd Get At A Pharmacy?
Yes. The Calquence shipped through the Patient Assistance Program is the identical FDA-approved brand-name medication dispensed through specialty pharmacies. It ships in the manufacturer’s original packaging.
Is There A Generic Version Of Calquence?
No. As of April 2026, Calquence remains patent-protected and no generic acalabrutinib is available in the United States. Alternative BTK inhibitors (ibrutinib, zanubrutinib) treat similar indications but are also brand-only drugs at similar price points.
Can I Get Calquence Through The PAP If I Have Medicare?
Possibly. Medicare Part D patients may be eligible for the Patient Assistance Program on a case-by-case basis. Medicare beneficiaries also benefit from the $2,100 annual Part D out-of-pocket cap in 2026. Our advocates review each Medicare patient’s situation individually to identify the most affordable pathway.
What If My Application Is Denied?
Our Patient Advocates will immediately explore every alternative — including manufacturer copay savings programs (for commercially insured patients), cancer-specific foundations (Leukemia & Lymphoma Society, PAN Foundation, HealthWell Foundation, CancerCare), Medicare Extra Help, insurance prior authorization appeals, and alternative BTK inhibitors with different coverage. If we can’t help, you won’t be charged.
How Long Does It Take To Get Approved?
Most oncology PAP applications are reviewed within 2 to 4 weeks. Because blood cancer treatment is time-sensitive, our advocates prioritize rapid processing and coordinate closely with your oncologist to ensure no gap in your Calquence therapy. We also explore bridge supply options if immediate access is needed.
Take Control of Your Medication Costs
Most oncology PAP applications are reviewed within 2 to 4 weeks. Because blood cancer
treatment is time-sensitive, our advocates prioritize rapid processing and coordinate
closely with your oncologist to ensure no gap in your Calquence therapy. We also explore
bridge supply options if immediate access is needed.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.